Heart & Brain Symposium 2018 - Scientific Program

Scientific Program


Preliminary Program

 Thursday, June 28, 2018

15:00 - 15:20
Welcome Address
Clayde Yancy, Northwestern University, Feinberg School of Medicine, USA 
15:20 - 16:50
SYMPOSIUM: ATRIAL FIBRILLATION – DETECTION, ASSESSING THE RISK AND TREATMENT
25%-30% of all ischemic strokes are of cardio-embolic origin where 45% are related to Atrial Fibrillation (AF). Strokes due to AF are devastating ones with high rates of mortality and disability. Therefore, detecting AF, assessing the stroke risk and tailoring the right preventive treatment to an individual patient is extremely important. This session will highlight and discuss all these important issues. 

Chairs: 
Clayde Yancy, Northwestern University, Feinberg School of Medicine, USA 
Shyam Prabhakaran, Northwestern University, USA
 
  • Advances in Detection of AF 
    James ReiffelColumbia University, USA
  • Assessing Stroke Risk in Subjects with AF
    Hooman KamelWeill Cornell Medical Center, USA 
  • Stroke Prevention in AF: The Role of Target-Specific Oral Anticoagulants
    Jonathan HalperinMount Sinai Medical Center, US.

Panel Discussion

16:50 - 17:00Short break
17:00 - 18:25
SYMPOSIUM: ATRIAL CARDIOMYOPATHY

Although AF is the widely discussed issue of cardio-embolic strokes other pathological conditions of the left atrium may be important as a source of embolism. This symposium will shed light on the so far "neglected" topic in cardio-embolic stroke. 

Chairs:
Jonathan Halperin, Mount Sinai Medical Center, USA
Clifford Kavinsky, Rush University Medical Center, USA
 
  • Atrial Cardiomyopathy Diagnostic Approaches
    David TirschwellUniversity of Washington Medicine Comprehensive Stroke Center, USA 
  • Fibrotic Atrial Cardiomyopathy 
    Jeffrey Goldberger, University of Miami Hospital, USA 
  • The Role of LAA Occlusion Devices in Stroke Prevention in Patients with AF
    Vivek ReddyDirector of Electrophysiology Laboratories at the Mount Sinai Medical Center, USA 

Panel Discussion

18:25 - 18:30Short break
18:30 - 19:00
KEYNOTE LECTURE:  THE HEART FAILURE PATIENT WITH STROKE - WHAT IS IMPORTANT, WHAT IS DIFFERENT?

Chairs:
Natan Bornstein, Shaare Zedek Medical Center, Israel
Jonathan HalperinMount Sinai Medical Center, USA
 
  • Wolfram Doehner, Vice Chair of the ESC Council on Stroke; Univ.-Prof. for Interdisciplinary Stroke Research Charite, Germany 
19:00Opening Ceremony 
Followed by a Networking Welcome Reception  


Friday, June 29, 2018

08:30 - 09:15
DEBATE SESSION: PFO –  WHO TO CLOSE?

Until recently PFO closure by endovascular procedure was not generally recommended. However, recently the results of 2 RTCs (CLOSE and REDUCE) and the long-term follow-up of the RESPECT trial were published. These results will have an impact on the current practice. The question now is not "should we close"? but "who to close"? This will be the scope of this debate.
 
Moderators:
Robert Hart, Mc Master University, Canada
Clifford Kavinsky, Rush University Medical Center, USA
 
1st Debater: Brett Cucchiara, University of Pennsylvania, USA
2nd Debater: Richard Smalling, UTHealth and Memorial Hermann Heart and Vascular Institute, USA 
09:15 - 10:00
PANEL DISCUSSION: COLLABORATIVE MEDICINE 

Moderators:
James Klaas, Mayo Clinic, USA
Christopher Granger, Duke University School of Medicine, USA

  • Wolfram Doehner, Vice Chair of the ESC Council on Stroke; Univ.-Prof. for Interdisciplinary Stroke Research Charite, Germany
  • James Klaas, Assistant Professor of Neurology, Mayo Clinic, Rochester, USA  
  • Carmelo GraffagninoDuke University School of Medicine, USA 
  • Hooman KamelWeill Cornell Medical Center, USA 
10:00 - 10:30
Coffee Break, Exhibition & Poster Viewing
10:30 - 12:00
INTERACTIVE CASE DISCUSSION

Moderators:
Frances Caprio, Northwestern University, USA
Milija Mijajlovic, Neurology Clinic, Clinical Center of Serbia

  • Shadi Yaghi, Brown University, USA 
  • MingMing Ning, Harvard Medical School, USA
12:00 - 12:45
DEBATE SESSION

It is greatly accepted that patients with Embolic Stroke of Unknown Source (ESUS) should go on long-term cardiac monitoring in order to detect sub-clinical AF. However, it is still unknown what is the burden of AF that is clinically relevant to trigger treatment with anticoagulants. This debate will highlight the various opinions: "small vs. extensive" is the dilemma that will be discussed. 

Moderator:

Farzaneh Sorond, Northwestern University, Feinberg School of Medicine, USA 
 
  • The Burden of AF to trigger treatment
    1st Debater: Jeff Healey, McMaster University, Canada
    2nd Debater: Rod Passman, Northwestern Memorial Hospital, USA 
12:45 - 14:15
Break, Exhibition & Poster Viewing
14:15 - 14:45
KEYNOTE LECTURE: NAVIGATE ESUS TRIAL: WHAT DID WE LEARN?

Chairs:
Jeffrey Saver, Geffen School of Medicine at UCLA, USA
TBC
 
  • Robert Hart, McMaster University, Canada 
14:45 - 14:50
Short break
14:50 - 16:40
SYMPOSIUM: COGNITION AND THE HEART
Cognitive impairment due to vascular pathology of the brain- Vascular Cognitive Impairment (VCI) is an important issue. Understanding the underlying and the related risk factors of VCI as well as the effect of the heart on VCI may have an impact on prevention and treatment of this condition. This symposium will discuss this issue from various aspects. 

Chairs:
Philip Gorelick, Thorek Memorial Hospital, USA
Georgios Tsivgoulis, University of Athens, Greece
 

  • The Neurovascular Unit and Cognitive Impairment
    Constantino Iadecola, Feil Family Brain and Mind Research Institute, USA
  • Hypertension, Small Vessel Disease and Cognition
    Ralph Sacco, Miller School of Medicine, University of Miami, USA
  • Defining Optimal Brain Health in Adults
    Philip Gorelick, Mercy Health Hauenstein Neuroscience Center, USA 
  • Aortic Stenosis, TAVR and Cognition: Imaging and Clinical Findings
    Ronald Lazar, University of Alabama at Birmingham, USA

Panel Discussion

16:40 - 17:10Coffee Break, Exhibition & Poster Viewing
17:10 - 18:40
SYMPOSIUM: EMBOLIC STROKE OF UNDETERMINED SOURCE
Stroke due to ESUS imposes difficult clinical dilemma for the treating physician. The magnitude of the problem, practical evaluation and treatment options will be discussed in this symposium. 

Chairs:
Ralph Sacco, Miller School of Medicine, University of Miami, USA
Rod Passman, Northwestern Memorial Hospital, USA

  • The Magnitude of the Problem
    Georgios Tsivgoulis, University of Athens School of Medicine/The University of Tennessee Health Science Center, Greece/USA
  • Evaluation of Patients with ESUS
    Jeffrey Saver, Geffen School of Medicine at UCLA, USA
  • Treatment options
    Gustavo SaposnikUniversity of Toronto, Canada
Panel Discussion


Saturday, June 30, 2018

08:00-09:00
EDUCATIONAL SESSION: BRAIN RECOVERY AFTER STROKE

Chair:
Natan Bornstein, Shaare Zedek Medical Center, Israel

  • Medical Therapy for Post-Stroke Motor Recovery
    Natan BornsteinShaare Zedek Medical Center, Jerusalem, Israel 
  • Intracardiac Hemostasis Parameters, Endothelial Damage and Their Association with Microembolization in the Fibrillating Atrium
    Laszlo Csiba,University Debrecen, Hungary 
  • Neuroprotection in the Reperfusion Era
    Jeffrey SaverGeffen School of Medicine at UCLA, USA  
09:00 - 10:30
SYMPOSIUM: ATRIAL FIBRILLATION: MISCELLANEOUS

There are several practical aspects in the treatment of AF patients with AC. This session will deal with three of these important topics as listed below.

Chair:
Jose Biller, Loyola University Medical Center, USA
TBC
 
  • How to Improve the Use of Anticoagulation for Stroke Prevention in AF
    Christopher GrangerDuke University School of Medicine, USA 
  • When to Start Anticoagulation after Acute Ischemic Stroke 
    Natan BornsteinShaare Zedek Medical Center, Jerusalem, Israel 
  • Treatment of Acute Stroke in AF Patients with Mechanical Thrombectomy
    Gregory AlbersStanford Stroke Center, USA
    Panel Discussion
10:30 - 11:00Coffee Break, Exhibition & Poster Viewing
11:00 - 11:30
KEYNOTE LECTURE: ATRIAL FIBRILLATION AND STROKE: THE FIRST 100 YEARS

Chairs:
Gregory Albers, Stanford Stroke Center, USA
Wolfram Doehner, Berlin Center for Regenerative Therapies (BCRT), Germany
  Robert HartMcMaster University, Canada 
11:30 - 13:00

INTERACTIVE CASE DISCUSSION

Moderator:
Laszlo Csiba, University Debrecen, Hungary
TBC

  • Kevin Sheth, Yale School of Medicine, USA 
  • Eitan Auriel, Carmel Medical Center, Israel 
13:00 - 14:00
Break, Exhibition & Poster Viewing
14:00 - 15:50

SYMPOSIUM: AF AND ICH

Anticoagulants (AC) are the treatment of choice for stroke prevention in AF patients. However, AC carries a risk of bleeding and especially of Intra-Cerebral Hemorrhage (ICH). Therefore, stroke prevention, acute stroke treatment of AF patients with Mechanical Thrombectomy and when to resume AC after ICH is of a major concern for the treating physician. This symposium will try to clarify these complex and problematic issues. 

Chairs:
Mahmut Edip Gurol, Massachusetts General Hospital Harvard Medical School, USA
James Connors, Rush University Medical Center, USA

 
  • Stroke Prevention in AF patients at High ICH Risk - Definition and Problems with Medical Management
    Edip GurolHarvard Medical School, USA
  • Reversal Agents
    John EikelboomMcMaster University, Canada
  • Perils of Combination Anticoagulant and Antiplatelet Therapy
    Edip GurolHarvard Medical School, USA
  • Resuming Anticoagulation after ICH
    Larry Goldstein, University of Kentucky, USA

    Panel Discussion
16:00CLOSING CEREMONY